What is your prediction for the derby?
We took our camera around Manchester to ask both United and City fans how they thought tonight's tussle would pan out.
As you'll see in our free video, there were some varied responses...
Discuss the derby with fellow Reds on our message board at manutd.com/talkingreds.
We took to the streets of Manchester to ask fans – of both a Red and Blue persuasion – for their predictions ahead of tonight's derby.
Unsurprisingly, the responses were widely contrasting: both sets of supporters are confident of picking up the points at Eastlands, though the scoreline is anybody's guess.
The Reds we spoke to claim City are inconsistent and vulnerable, while Blues insist their side will be too strong for what could be a depleted United line-up.
After watching their opinions in our free video above, why not have your say on our message board at manutd.com/talkingreds?
And if you're coming to Manchester, even when there isn't a match on, be sure to look out for our cameras and have your views at the ready.