United are 1/6 to secure a victory away to the Premier League’s bottom club Derby, which would put the Reds top of the table ahead of Arsenal, whose clash with Middlesbrough kicks off at 17:15 GMT.

Derby are 10/1 to claim only their second win of the season, and it’s 5/1 for a draw, which indicates the task facing Paul Jewell's men, who were battered 6-1 on Wednesday against United's title rivals Chelsea.

Sir Alex Ferguson’s side are unbeaten in the last seven away matches against the Rams and won 4-1 at Old Trafford in December. It’s 12/1 for a repeat of that scoreline.

Ryan Giggs, who scored the opening goal that day, has missed United's last four games but could return for the visit to Pride Park. He is 15/2 to grab the first goal again and 70/1 to do so in another 4-1 success.

Cristiano Ronaldo, just two goals short of George Best's 32-goal haul in 1967/68, is 11/4 favourite to notch the opener, with Wayne Rooney 3/1 and Carlos Tevez, who bagged a brace against Derby earlier this season, 4/1.

Going into this weekend’s matches United are 4/7 to retain the Premier League title, Arsenal are