United kick off the 2012/2013 season at Everton with Wayne Rooney likely to be hunting another goal against his former club.
The England striker was the Reds' first Barclays Premier League goalscorer in both 2011 and 2009 and will be aiming to get off to another flier at Goodison Park.
Can you recall the last FIVE players, aside from Rooney, to score the opening goal of United's league campaign?
Click here for the answers and look out for another question next Thursday.
More United-based trivia questions: Old Trafford penalties | England's seven Reds | Alan Hardaker Trophy winners | Scored against United | United stars at European Championship | Goals for England | The name game