The Argentinian striker volleyed home Nani's near post corner in the 93rd minute, cancelling out Dimitar Berbatov's first-half opener for the Londoners.
The Bulgarian striker converted from close range after 20 minutes, pouncing after Edwin van der Sar could only parry Aaron Lennon’s cross into his path.
United’s goalkeeper vehemently contested the goal’s award, maintaining that Jermaine Jenas had handled the ball in the build-up, although his protests only earned one of nine bookings dished out by referee Mark Clattenburg.
The draw – United’s fourth league stalemate of the season – always looked to be the best the Reds could hope for after a sluggish start. Tottenham, for their part, were vibrant from the very first whistle.
Nemanja Vidic had to be alert and athletic to prevent a long pass from Tom Huddlestone reaching Berbatov inside the first five minutes and, although Wes Brown did miss with a speculative shot for United, the hosts made all the early running.
Owen Hargreaves did superbly to turn away a dangerous cross from Berbatov after 15 minutes, but the England international was unable to prevent Spurs taking the lead five minutes later.