At the other end, the ever-energetic Rafael collected a defence-splitting pass before cutting inside and shooting, but his effort was straight at substitute keeper Nick Rimando.
Deafening screams echoed round the stadium just after the hour-mark when Chicharito entered the fray in place of Nani for his United debut. Proceedings didn’t get off to the best start, however, when a David Ferreira free-kick was headed home from close range by fellow substitute Brian Ching seconds later.
Chicharito wasn’t about to be upstaged though and he almost opened his Reds’ account soon after. Rafael’s good run and cross was met at the back post by the Mexican who blasted a low drive goalwards only to see it turned away by the feet of Rimando.
The American stopper had no chance with substitute Darron Gibson’s free-kick on 70 minutes which was curled beautifully inside Rimando’s right-hand post from 20 yards to restore United’s two-goal advantage.
Three minutes later, Tom Cleverley, who had earlier replaced Obertan, netted a sublime second goal of the tour and the Reds' fourth of the night. Fletcher’s clipped pass over the top was brilliantly flicked over Wilman Conde by Cleverley who then turned and volleyed the ball home in one movement from three yards out.
The loudest cheer of the night came six minutes from time when Chicharito claimed United's fifth in glorious fashion. A measured ball over the top from Fletcher was picked up by the Mexican who let the ball bounce before looping it over Rimando into the far corner from the edge of the box.