|1||Van der Sar|
Chelsea's response was instant, with Van der Sar palming away a Kalou header and Branislav Ivanovic only finding the side-netting from the rebound. Van der Sar became more prominent as Luiz moved forward with menace to test the veteran, who then dived to his left to frustrate Didier Drogba from a free-kick.
Another cheaply-awarded foul allowed Drogba a second set-piece attempt before there was controversy when Ivanovic escaped a second booking for a blatant foul on Rooney.
Undeterred, United finished the half strongest. John Obi Mikel prodded behind following a Valencia one-two with Rooney and the Ecuadorian winger smashed over the top following neat play by Giggs and Fabio.
Malouda had the first real effort of the second period but Van der Sar watched it sail wide before another big decision went against United. Lampard clearly handled Valencia's cross inside the area but Howard Webb waved play on as everybody anticipated the official pointing to the spot.
Carlo Ancelotti introduced Fernando Torres to his attack just past the hour mark as the Blues searched for a route back into the game, and the title race.
Valencia had another penalty shout rejected after tussling with John Terry inside the box following another rapid break but, this time, it was probably the correct decision from referee Webb.
Van der Sar had to be alert to field a long-range drive by substitute Alex and Drogba was penalised for handball when delivering a shot wide of the far post as some pressure started to build on the home goal.