Adam Bostock reviews each player's performance...
David De Gea: The goalkeeper could fill this ratings report on his own, after his outstanding performance gave United a glimmer of hope for the second leg. He made a variety of stops, not just trademark flying saves like the one from Iker Munaian early in the second half, but also some vital blocks.
Rafael: The Brazilian will surely bounce back from a tough night, and learn from the momentary switch-off that allowed Muniain to bag the killer third goal.
Chris Smalling: Eight days after his head injury with England, Smalling could have picked an easier opponent than Fernando Llorente. Beaten for a header that flew just wide on the half-hour mark, he slipped just before the big striker levelled the scores. He had to leave the field early in the second half when his Wembley wound re-opened.
Jonny Evans: Despite the scoreline, the centre-back was possibly United’s best outfield player, putting in some excellent changes and bringing the ball forward when he could. His only noticeable blemish was allowing Markel Susaeta to outpace him for a one-on-one in the first half; mercifully the midfielder missed the target.
Patrice Evra: Besieged early on as Athletic Club attacked down his flank, the skipper inadvertently played a major role in their third goal – he was penalised rather harshly for passing the ball without his boot on.
Ashley Young: Starting on the right, he was one of United’s livelier threats in the first half when counter-attacking opportunities presented themselves. Tracked back well and had to - but unlike in recent games