The most recent league fixture was a goalless draw at Selhurst Park in March 2005.
Manager: One of the most quotable and eccentric managers in the country, Ian Holloway has already run foul of authority this season. He will be confined to the stands at Old Trafford on Saturday as he serves the first of a two-match touchline ban for his comments following Palace’s defeat to Spurs last month.
Star man: Striker Marouane Chamakh joined Palace on a one-year deal in the summer after a largely disappointing three years with Arsenal, and he was on target in the Eagles' defeat at Stoke. Jason Puncheon, on loan from Southampton, can be a tricky customer and Dwight Gayle, signed from Peterborough after a prolific rise through the divisions, could also provide a goal threat.
Sub-plot: New signing Marouane Fellaini will be available for United for the first time since his move from Everton transfer deadline day. Wilfried Zaha, yet to feature for United in the Premier League this season, left Palace in January but was immediately loaned back and helped the Eagles secure promotion via the play-offs. The England Under-21 winger was part of the Palace side that knocked United out of the Carling Cup in 2011.
Did you know? Russell Beardsmore was United’s goal scorer the last time the Reds lost to Palace in the league at Old Trafford, a 2-1 defeat in December 1989, the same season United won the FA Cup by beating Palace in a replay at Wembley.