The manager: After serving his apprenticeship with stints as coach or assistant manager at Newcastle, Chelsea, West Ham and Liverpool, Steve Clarke stepped up as a number one for the first time when he succeeded Roy Hodgson at the Hawthorns in the summer of 2012. The Scot had a good first season in charge, guiding West Brom to eighth place, their best finishing position since 1981.
Star man: The enigmatic Nicolas Anelka has yet to trouble the scorers since returning to English football this summer, but the experienced French striker certainly has the potential to pose problems for United's defence.
Sub-plot: United fans may choose to remind Anelka about his penalty miss in Moscow which sealed victory for the Reds in the 2008 Champions League final.
Did you know? West Brom have not won at OT since an epic 5-3 win in December 1978, when they were managed by future Reds boss Ron Atkinson. One of the goal scorers that day was the late Laurie Cunningham, who played five times for United while on loan from Real Madrid in 1983.
Referee: Michael Oliver. The 28-year-old Northumberland-based official, who was in charge for the 5-5 last season, has brandished 11 yellow cards in three Premier League matches so far this season.
Quote/unquote: "I’ve never been afraid of going to Old Trafford. You have to relish it because it’s fantastic. You go there, you go on the pitch, look at the crowd and it makes you feel good. It should make you ready to play the best you can. I don’t hold with the fear factor or the thought that you should go to these places and be intimidated. You should go there and relish the challenge." Steve Clarke, West Brom manager.