Date, time and coverage: Saturday 5 April, 15:00 BST. The match will not be shown live in the UK. You can follow it live via ManUtd.com's rolling blog and MUTV Online's radio commentary. Video highlights will be available from midnight BST on matchday.
Form guide: United head into this match boosted by last weekend’s 4-1 win over Aston Villa and the midweek Champions League draw with Bayern Munich, two results that have lifted the confidence and belief of everybody associated with the Reds. As such, David Moyes is hoping to maintain the feel-good factor at St James’ Park ahead of Wednesday's blockbuster second leg in Germany and the manager will no doubt be encouraged by the fact that Newcastle have lost their last two Barclays Premier League fixtures - conceding seven goals in the process. However, memories of December’s 1-0 defeat at Old Trafford are still relatively fresh in the mind.
Ins and outs: The boss has injury problems in defence with Jonny Evans, Chris Smalling, Rafael and Alex Büttner all carrying knocks, while his options further forward are limited by Ryan Giggs and Robin van Persie also being unavailable. Patrice Evra and Juan Mata should both return after missing Tuesday’s European match through suspension and ineligibility. Meanwhile, Newcastle are set to be without Mathieu Debuchy, Moussa Sissoko, Loic Remy and goalkeeper Tim Krul, plus long-term absentees Shola Ameobi, Ryan Taylor and ex-Reds winger Gabriel Obertan.
Newcastle's last XI: Elliot; Yanga-Mbiwa, Williamson, Coloccini, Haidara; Sissoko, Anita, Tiote, Gouffran; Ben Arfa, Cisse.