Date, time and coverage: Saturday 22 February, 17:30 GMT. The match will be broadcast live on Sky Sports in the UK. Follow the action live via ManUtd.com's rolling blog and MUTV Online's radio commentary. Match highlights will be available on MUTV Online from midnight GMT.
Form guide: The Reds are without a win in three games, but last time out a gritty performance away to Arsenal earned a valuable point. Palace looked doomed when Tony Pulis took the managerial reins in November, but a marked upturn in form has seen them move out of the relegation zone. It's still tight near the foot of the table, but Palace have only lost once in seven home games under their new manager and are displaying all the resilience that Stoke became renowned for under Pulis.
Ins and outs: Marouane Fellaini was an unused sub in the draw with Arsenal and could make his return after two months away, while Rafael will have been closely monitored following his concussion at Emirates Stadium. The Eagles bolstered their squad when they swooped for five players on transfer deadline day, including winger Tom Ince, son of former United midfield enforcer Paul. Ince junior and fellow new-boy midfielder Joe Ledley both scored on their debuts in the 3-1 win over West Brom last time out as Palace claimed the spoils in a relegation six-pointer.
Last meeting: Victory over Palace in September at Old Trafford gave David Moyes his first home win as Reds boss, with a penalty from Robin van Persie and a late free-kick from Wayne Rooney condemning the south London side, then managed by Ian Holloway, to a 2-0 defeat.