Date, time and coverage Tuesday 25 February, KO 19:45 GMT. The match will be broadcast live on ITV in the UK. Follow the action live via ManUtd.com's rolling blog and MUTV Online's radio commentary. Match highlights will be available on MUTV from midnight GMT.
Form guide Saturday's 2-0 win at Crystal Palace means United go to Greece on the back of a three-match unbeaten run. However, the record of Tuesday's opposition in the Greek Super League – which they top by 20 points – reads won 24, drawn two, lost none. Olympiacos' most recent outing saw them rack up a 4-0 away win at OFI Crete.
Ins and outs Juan Mata's appearances for Chelsea in the Champions League earlier this season count the Spanish playmaker out for the trip to the Greek capital. Phil Jones and Jonny Evans have not travelled but Rafael is available following his recent concussion. Experienced Argentinian forward Javier Saviola could miss out for the home side with a thigh strain sustained in their win at the weekend.
Last meeting The Reds faced the most successful club in Greek history – they have won the league title 40 times and are reigning champions – at the group stage in the 2001/02 and 2002/03 campaigns, winning all four meetings. The last was a see-saw battle at the Georgios Kamaras Stadium in Rizpouli, in which the hosts clawed back a two-goal deficit in the second half, only for Paul Scholes to secure victory.
Betting There's not a lot to choose between the two sides with Bwin, our official betting partners, who make the Reds favourites at 2.05. The home side are 3.60 to win, while the draw is 3.30, but Adnan Januzaj is a tempting 34.00 to get his first goal in the Champions League in a 1-0 win for the Reds.