Form guide: United need to bounce back quickly from Tuesday's derby defeat, while Villa are sure to be smarting from their 4-1 loss at home to Stoke last Sunday. The Villans' inconsistency has hampered their season - in the previous week, they inflicted a rare defeat on title-chasing Chelsea.
Ins and outs: Robin van Persie is absent for a few more weeks because of a sprained knee, but while defenders Jonny Evans and Chris Smalling missed the derby through injury, Nemanja Vidic is available again after a two-match suspension.
Betting: The Reds are short-priced favourites to win at 1.40 with bwin, United's official betting partners. The draw is 4.40 while Villa are a distant 8.00 to claim all three points.
Last meeting: Villa were clinically swept aside in December, with two goals from Danny Welbeck within three first-half minutes giving United a comfortable cushion before Tom Cleverley pounced just after half-time to effectively end the game as a contest.
Villa's last line-up: Against Stoke, goalkeeper Brad Guzan lined up behind a back four of Leandro Bacuna, Ron Vlaar, Nathan Baker and Ryan Bertrand. The midfield consisted of Karim El Hamadi, Ashley Westwood and Fabian Delph, behind a front three of Andreas Weimann, Christian Benteke and Gabby