Date, time and coverage: Sunday 11 May, 15:00 BST. There will be no live TV coverage in the UK. Follow the action live via ManUtd.com's rolling blog and MUTV Online's radio commentary. Match highlights will be on MUTV Online from midnight GMT.
Form guide: Since Ryan Giggs took temporary charge of the first team on 22 April, the Reds have won two games and lost one. The Welshman began his tenure in a manner most befitting of his attacking style as United swept past Norwich 4-0. A flat performance against Sunderland followed, resulting in a disappointing 1-0 reverse, before a 3-1 win against Hull City in the final home game of the season gave the Old Trafford crowd some kind of tonic after a tough campaign. Southampton, who currently sit only one place behind United, enter this game on the back of two straight wins after an impressive 2-0 triumph against Everton was preceded by a similarly efficient display at Swansea. The Saints battled to a solid 1-0 away win in Wales thanks to a last-minute Ricky Lambert strike.
Ins and outs: Both Phil Jones (shoulder) and Wayne Rooney (groin) are likely to miss out after recent injuries but Ryan Giggs otherwise has a fully fit squad to choose from. For the Saints, Gaston Ramirez could return after a spell on the sidelines but the match is likely to come too soon for Japanese international Maya Yoshida. Long-term absentee Jay Rodriguez and substitute stopper Kelvin Davies are also out.
Betting: Club betting partner bwin has both sides closely priced to take the spoils on Sunday. United are slight favourites on 2.45 with the Saints close behind at 2.75 and the draw priced at 3.30. As the last two meetings between the sides yielded close results – a 2-1 win at Old Trafford in 2012/13 and a 1-1 draw earlier this season – why not take a punt on Under 3.5 goals, priced at 1.40?