Who are the key men for Sunday's trip to Stamford Bridge?
We put that question to supporters at Old Trafford and captured their responses on camera, as you can see here in our free video.
The discussion continues on our message board at manutd.com/talkingreds.
With Rio Ferdinand ruled out, Jonny Evans is likely to deputise and given his display at Stamford Bridge last season he may emerge as an important figure in the Reds' backline.
Have your say on who will be United's main men at manutd.com/talkingreds.