Who are the key men for Sunday's trip to Stamford Bridge?
We put that question to supporters at Old Trafford and captured their responses on camera, as you can see here in our free video.
The discussion continues on our message board at manutd.com/talkingreds.
It might only be November but all the fans interviewed ahead of the trip to Chelsea agreed on the significance of Sunday's clash. Where they differed was on the subject of United's key players.
There were plenty of names in the mix - Wayne Rooney showed his worth once again by inspiring the Reds to a comeback against CSKA Moscow, Darren Fletcher has shown his ability in the big games, netting twice in the Manchester derby at Old Trafford, and Dimitar Berbatov has found his scoring touch, netting superbly against Sunderland and Blackburn.
With Rio Ferdinand ruled out, Jonny Evans is likely to deputise and given his display at Stamford Bridge last season he may emerge as an important figure in the Reds' backline.
Have your say on who will be United's main men at manutd.com/talkingreds.