Andy Cole's the only other Red to have achieved the feat since the inception of the Premier League. He bagged five in United's 9-0 win over Ipswich Town in March 1995 and you can watch those goals in the video player above.
Berbatov and Cole aren't the only men to have netted five or more for the Reds. George Best famously hit six in an 8-2 win against Northampton Town in 1970, while Harold Halse bagged half-a-dozen almost 60 years earlier as United beat Swindon Town 8-4 in the 1911 Charity Shield. And the man they called Gunner, Jack Rowley, hit five when United beat Yeovil Town 8-0 in the FA Cup in February 1949.