Two weeks earlier, Sir Alex's men had lost the first leg 3-1, meaning United required at least a two-goal win to have any chance of progressing. And from the off, Real goalkeeper Iker Casillas was under siege.
Alas, United's open commitment to attack left gaps and it took just 12 minutes for Zinedine Zidane to thread a perfect ball through for Brazilian striker Ronaldo to fire inside Fabien Barthez's near post.
Ruud van Nistelrooy levelled just before the break but Ronaldo struck two more goals to complete his hat-trick (and earn a standing ovation from the home support when he was substituted).
The Reds then scored twice more but it still wasn't enough. United, in thrilling yet heartbreaking fashion, were out.
You can watch our 11-minute extended highlights package above.
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