Stoke skipper Ryan Shawcross had only two senior (League Cup) outings for boyhood club United, but has served the Potters with distinction since a loan move was made permanent in January 2008.
Alongside Ryan, four other ex-Reds have made at least a century of league appearances for United's next opponents...
Stoke (276 league apps, 76 goals). United (97 league apps, 26 goals).
United's hero of the 1977 FA Cup campaign had earlier etched himself into Potters legend as the spearhead of the side that won the 1972 League Cup – Stoke's only major trophy success – and reached consecutive FA Cup semi-finals in 1971 and '72.
United (342 league apps, 57 goals). Stoke (133 league apps, 14 goals).
McIlroy famously netted on his debut against Manchester City, aged 17, but 11 years on he also scored on his Stoke debut, after starring for Northern Ireland in the 1982 World Cup, and spent three years in a side Potters fans rate as one of their most entertaining.
United (259 league apps, 59 goals). Stoke (182 league apps, 59 goals).
This Busby Babe survived Munich and recovered fully to resume his career as a prolific forward and playmaker. Sold to Stoke six months before Denis Law's arrival from Torino, Viollet scored 66 goals in all competitions during five seasons at the Victoria Ground.
Stoke (147 league apps, 48 goals). United (7 league apps, 2 goals).
Now a familiar TV pundit, Stoke-born Crooks began his career at his hometown club. He only spent six weeks at United – a loan spell in the winter of 1983/84 – but bagged a couple of goals to help keep the Reds on the heels of league leaders Liverpool.