2000: Southampton (A) 3-1, Chelsea (H) 3-2
United clinched the title at The Dell with three goals inside the opening half-hour. David Beckham, a Francis Benali own goal and Ole Gunnar Solskjaer did the damage. There was no let-up from the champions as Dwight Yorke (2) and Solskjaer ensured the hosts shaded an entertaining clash with Chelsea.
2006: Sunderland (H) 0-0, Tottenham (A) 2-1
A surprise goalless stalemate with the Premier League's basement side, effectively ended United's hopes of another title. The Wearsiders were relegated as a result of the draw, in any case, but Sir Alex's team recovered to win at White Hart Lane with a Wayne Rooney double.