1989: Nott'm Forest (H) 0-1
1990: Sheff United (A) 1-0
1994: Charlton (H) 3-1
1995: QPR (H) 2-0
1996: Southampton (H) 2-0
1999: Chelsea (H) 0-0, 2-0
2004: Fulham (H) 2-1
2005: Southampton (A) 4-0
2007: Middlesbrough (A) 2-2, 1-0
2008: Portsmouth (H) 0-1
2009: Fulham (A) 4-0
2011: Arsenal (H) 2-0
With Chelsea next on the agenda for United in the FA Cup, we take a look at Sir Alex's record in the last eight of the competition.
Sunday's clash will be the 13th at this stage for the boss since he replaced Ron Atkinson at the Old Trafford helm.
Here's our shortlist of the five top last-eight ties... which one was your favourite?
1994: Charlton (H) 3-1
This home clash en route to a first-ever Double was far from straightforward following Peter Schmeichel's sending off. The Dane was dismissed for handling outside his box at the end of the first half but Les Sealey came on and the 10 men still triumphed with Mark Hughes, at the second attempt, and an Andrei Kanchelskis double seeing off the Addicks, who replied through Carl Leaburn.
1999: Chelsea (A) 2-0
After a goalless draw at Old Trafford, many predict the wheels would come off the Treble bid at Stamford Bridge. However, Dwight Yorke volleyed past Ed Goey early on and then added a superb second close to the hour-mark. Peter Schmeichel stood