With Manchester United preparing for a 250th fixture in Europe's premier competition, we cast an eye over some of the best individual performances by Reds over the years...
1. George Best vs Benfica (A) 5-1, 09.03.1966
'El Beatle' was born on a magical night in Lisbon when he tore the much-vaunted hosts to shreds. The wing wizard had already scored a header when he embarked on a solo dribble that yielded one of his personal favourite goals. The torment continued for the Benfica defence as an incredible scoreline was racked up. "It was surreal stuff," Best enthused. "To be a part of such an experience was unreal."
2. Roy Keane vs Juventus (A) 3-2, 21.04.1999
The Reds captain may have shrugged off Sir Alex Ferguson's accolade that he "covered every blade of grass" this night by claiming it was merely his job (likening it to a postman delivering letters), but it was the manner of Keane's performance that said everything about the inspirational Irishman. Despite collecting a yellow card that ruled him out of the final, he headed in a David Beckham corner to reduce the deficit and led his side to the most remarkable of comebacks.
3. Cristiano Ronaldo vs Arsenal (A) 3-1, 05.05.2009
On a beautiful, sunny evening in the capital, the stupendous free-kick from long-range that deceived Manuel Almunia was brilliant in itself. However, the breakaway strike to make it 3-0 on the night (4-0 on aggregate) was even better and thrilling in its execution. Proving to be the best player in the world, Ronaldo was simply too hot for the Gunners to handle.