Fifty years on, we are celebrating three of the greatest players in the Reds' history with a video showing the trio at their finest, tearing apart opposition defences and scoring plenty of goals.
With differing styles, they complemented each other perfectly. Charlton was known for finding the net with thumping efforts from distance, a style which helped him to become United's all-time record scorer, with 249 strikes in his 758 appearances.
Second on that scorers' list is Law, who netted 237 goals in 404 games. He was a renowned goal-poacher; always in the right place at the right time and clinical in a one-on-one situation.
And then there's Best. His mazy runs and superb dribbling skills became a hallmark of his time at Old Trafford and made him almost unstoppable. He scored 179 times across 470 appearances.
Now you can relive some of their finest moments, which included helping to win two First Division titles and the club's first European Cup, by watching our video above.