Live broadcasts from the Reliant Stadium, Houston begin at 19:30 CDT (local time) Wednesday or 01:30 BST (UK time) Thursday.
Please note, only subscribers in the UK and Republic of Ireland will be able to watch the match live on MUTV Online. Highlights will be available to view everywhere except Hong Kong and Malaysia from 04:30 BST. (Read more on geographical restrictions here).
United team: Van der Sar; Rafael, Brown, J.Evans, Fabio; Nani, Fletcher, O'Shea, Obertan; Giggs, Macheda.
Highlights and reaction to the Reds' previous tour matches, including Sunday's game against Kansas City Wizards, are available to view on-demand on MUTV Online.
Match coverage on ManUtd.com
Gemma Thompson is on tour with United - you'll be able to read her match report and see photos on ManUtd.com from full-time, followed by quotes from Sir Alex Ferguson and his squad. All of the above can also be read on your mobile phone at wap.manutd.com, which offers a text alert service informing you of the result and the Reds' scorers.