Date, time and coverage: Tuesday 1 January, 15:00 GMT. There’s no live TV coverage in the UK. Follow the action live via ManUtd.com’s radio and text commentary.
Form guide: The Reds are unbeaten in the last eight league games and won both festive fixtures at Old Trafford (4-3 v Newcastle, 2-0 v West Brom). Wigan, on the other hand, have won just one of their last seven matches... although it was their most recent fixture, away at Aston Villa. Against United, the Latics can boast a recent win at the DW Stadium but last seaon's result was the only win they've ever achieved against Sir Alex's men.
Betting: Given the sides' form, it's no surprise to see United as heavy 53/100 favourites with bwin. Wigan are 5/1 to notch a home win, while the draw is priced at 3/1. If you fancy a Reds romp you can get 17/1 on United winning 4-0 and 3/1 on Robin van Persie scoring the first goal of the game.
Ins and outs: Sir Alex will inevitably shuffle his pack for what is the Reds' fourth game in 10 days. Wayne Rooney, Anderson and Nani are out through injury, although Rafael and Phil Jones are likely to return. Shinji Kagawa played against West Brom after a long break, while Robin van Persie, Javier Hernandez, Paul Scholes and Ryan Giggs should all be fresh after being rested against the Baggies. Wigan are without Adrian Lopez, Ryo Miyaichi, Ben Watson and Albert Crusat, although Roberto Martinez was able to welcome Ivan Ramis back to action on 29 December.
Last meeting: United beat Wigan 4-0 at Old Trafford back in September in a game that featured goals by debutants Alexander Büttner and Nick Powell. The last time at Wigan was a different story, however. The Latics won 1-0 that night, a result that severely dented the Reds' chances of winning last season's Premier League.