Sub-plots: Antonio Valencia and Tom Cleverley have both spent time at Wigan and would no doubt love to score against their former club. Meanwhile, Javier Hernandez will hope to add to his impressive scoring tally against the Latics: he's netted four in five previous appearances.
Whistle-blower: Andre Marriner will take charge of United's trip to Wigan and it's the first time he's officiated the Reds since the opening day of the season when Sir Alex's men lost 1-0 at Everton. In the 15 matches he's refereed this season, he's yet to issue a single red card.
Rivals watch: Manchester City host Stoke (also 1 January 15:00 GMT), while Chelsea meet Queens Park Rangers in a West London derby 24 hours later (2 January 19:45 GMT)