The webchat will start at approximately 12:30 GMT, subject to Manchester United's training schedule, and your questions are welcome then – during the chat – or in advance at www.manutd.com/webchat.
There's plenty you could ask Ashley and Danny after a dynamic start to the 2012/13 season, peaking so far in the Reds' 3-2 win over title rivals Manchester City in which both men played a part. They've also had a busy calendar year on the international stage, as key members of Roy Hodgson's England squad.
Your questions are not limited to matches for club and country, though. If there's something you'd like to know about the players' lives off the pitch, ask away.
Please bear in mind, we expect to be inundated with submissions, so we'll be on the lookout for questions that stand out from the crowd. As an added incentive, the fan who sends in the best question – as selected by Ashley and Danny – will win a shirt signed by the two players.