With the games taking place at Preston North End's Deepdale and Rochdale's Spotland, United fans are being encouraged to attend and support the potential stars of the future.
Michael Keane has earned his first call-up for the Three Lions after previously representing Republic of Ireland at youth level. Meanwhile twin brother Will Keane is looking to add to his record of one goal in six games for Noel Blake's team.
Barclays Premier Reserves League play-off hero Sam Johnstone is one of two goalkeepers in the squad - Middlesbrough's Connor Ripley being the other - while another of Warren Joyce's successful squad, versatile defender Tom Thorpe, was also called up as a replacement for Luke Garbutt of Everton. There would have been five Reds involved had Larnell Cole not withdrawn through injury.
Speaking about brother Michael's selection, Will Keane said in the Manchester Evening News: "It’s great for our family that we’re both playing for England now as they can now support the same team and our mum and dad are really proud of what we’ve done so far. I’m sure we’ll be rooming together as it’s Michael's first time in the squad."
England's first match, against Slovenia at Deepdale, is on Friday 25 May, with Montenegro at Spotland on Sunday before Switzerland at Deepdale rounds off the series next Wednesday 30 May. For ticket information, see Rochdale and Preston's official websites.