Both strikers missed their international commitments in midweek but van Persie should be fine to face the Canaries after resting a thigh problem.
Rooney, however, could be sidelined after hurting his ankle at Aston Villa and Jonny Evans may sit out his second successive Reds match with the groin injury that also forced him out of Northern Ireland's World Cup qualifier with Azerbaijan.
"We've still got some doubts about Wayne and Jonny Evans," said Sir Alex. "I think Robin should be fit. We'll see what they are like today but there is a doubt.
"Phil Jones has been training all week. We will take him to Turkey [to play Galatasaray in the Champions League] with us. He’ll get part of it there, which is a good start for him."
"Bringing on Chicharito [at Villa] was good for us and he should start tomorrow."