Opposition boss: Andre Villas-Boas was sacked as Chelsea manager after just nine months at the helm. Undeterred, the highly-regarded Portuguese soon found employment with Tottenham after Harry Redknapp was surprisingly relieved of his duties in June. Since then, the former Porto boss has started something of a revolution at White Hart Lane by recruiting new boys Clint Dempsey, Hugo Lloris, Moussa Dembele, Jan Vertonghen and Gylfi Sigurdsson and signing last term's loanee Emmanuel Adebayor on a permanent deal.
Star man: Amid all the comings and goings, striker Jermain Defoe remains Tottenham’s primary attacking weapon and is likely to test United’s injury-ravaged defence on Saturday. The England international has already scored four times this season, two with each foot, during a blistering start to the campaign and could bag his 200th career goal at OT.
Sub-plots: Villas-Boas will be hoping for better luck against United after last season's 3-1 defeat at Old Trafford - when Torres missed an open goal at the Stretford End - and 3-3 draw at Stamford Bridge when the Reds came back from 0-3 down.
Did you know: It will be 11 years to the day on Saturday since United came from 3-0 down to beat Spurs 5-3 in North London, thanks to second-half goals from Andy Cole, Laurent Blanc, Ruud van Nistelrooy, Juan Sebastian Veron and David Beckham.
Quote/unquote: "Villas-Boas has a challenge. He wasn't at Chelsea very long, but in the time he was there, his team tried to play football. That's his philosophy and I think he's carrying that out at Tottenham as well. He suits Spurs. They've always