David De Gea started on the bench after the Dane was outstanding a midweek run-out at Under-21 level although the manager admits the Spaniard will return for the visit of Wigan in the next Barclays Premier League outing.
"I think young David made a mistake last week [against Fulham]," he told Sky Sports. "He knows it. With the form he's been in, he's been making some fantastic saves, but one error like that could have cost us the game.
"It's just a learning process for him and he'll be back in a couple of weeks' time."
Rio Ferdinand also returned to the side at the heart of the defence, alongside Nemanja Vidic.
"Michael Carrick did a job and did really well but he's back in midfield and I'm delighted," added the boss. "Rio's experience at the back should give us a little more solidity."