Date, time and coverage: Monday 22 April (kick-off 20:00 BST). The match will be shown live in the UK on Sky Sports and you can follow it via ManUtd.com's exclusive text and radio commentaries at tracker.manutd.com.
Form guide: Aston Villa may find themselves in a relegation scrap, but the Midlanders have lost just one of their last five fixtures, winning three and drawing one. Their form has come just at the right time, although they go into this round of fixtures just one spot and three points above the relegation zone. Meanwhile, United's march towards the end of the season has slowed somewhat. Just one win in four fixtures represents the Reds' worst form of the campaign. Of course, Sir Alex's men still hold a 13-point lead over rivals Manchester City, and after the Blues lost 3-1 at Tottenham on Sunday United now have a chance to win the title on Monday.
Ins and outs: Former Villa winger Ashley Young has been ruled out for the rest of the season with an ankle injury, while Monday's match is expected to come too soon for Paul Scholes, who's still recovering from a knee injury. Villa will be sweating on Gabriel Agbonlahor's fitness (thigh), but Chris Herd (ankle), Marc Albrighton (ankle), Gary Gardner (knee) and Richard Dunne (groin) are all ruled out.
Betting: The Reds are bwin’s 11/50 favourites to pick up three points. Villa can be backed at 19/2 but just one win in their last 28 visits to Old Trafford will be enough to deter most punters. If you fancy Javier Hernandez to score the first goal (remember, he netted twice at Villa Park earlier this season), he’s priced at 4/1. Find more odds and place bets with the Reds' official betting partner at www.manutd.com/bet.