Moyes admired ex-Old Trafford idol van Nistelrooy during his time as Everton manager and can see similarities in the way that van Persie goes about his business in the Reds shirt.
"Robin's movement and his understanding of the game with his hold-up play and movement in the box is sensational," declared Moyes. "It really is top-notch.
"There are some things I don't even know if you can coach, nearly instinctive things that you pick up if you're a top player. I used to wonder how Ruud van Nistelrooy scored as many goals as he used to get. I think he was an unbelievable goalscorer.
"I used to show my centre-forwards and ask how did van Nistelrooy score, how did he do it? But Robin has got a little bit of that as well, something different. An ability to score all different types of goals."
Van Persie enjoyed his first campaign at Old Trafford, top scoring in the Barclays Premier League, and has already netted four times in the first two competitive fixtures of 2013/2014.
"I have to say, ever since he joined up in Sydney, he's been terrific," said Moyes. "We've tried to look after him