Wayne Rooney's fitness will be assessed ahead of Saturday's Barclays Premier League clash with West Ham but Nani is out with a hamstring problem.
United manager David Moyes has reiterated that Rooney still has a chance of being involved against the Hammers after missing the midweek Capital One Cup win at Stoke City with a groin injury.
"Wayne has got a chance," stated the boss during Friday's press conference at the Aon Training Complex. "So we will see how he is tomorrow. Nani has got a hamstring injury and we were worried about that. It's worse than we hoped so that might well keep him out for a few weeks."
Some of the Reds' fringe performers impressed at Stoke to give Moyes more food for thought regarding his team selection for the Old Trafford encounter this weekend.
"The players have done really well," added the boss. "That is why there is such a good squad and a big squad here because throughout the season, the amount of games we have to play here, you do need those extra players.
"We have seen recently, in the last couple of games, we have been a little bit short in areas but the players who have come in have done brilliantly well. We have needed the whole squad, we really have. Even bringing Darren Fletcher back into it as well has given everybody a lift. But not only that, for Darren to get a couple of games and come back into the team is great."