The Reds can open up a 10-point lead at the Barclays Premier League summit with victory away to Fulham ahead of Manchester City's clash with Liverpool on Sunday. The manager firmly believes he has enough depth and talent at his disposal to challenge for all the top honours with Real Madrid and Reading up next in the Champions League and FA Cup respectively.
After utilising his squad to good effect thus far, decisions are going to prove difficult with the games continuing to come thick and fast but Sir Alex will have no qualms about throwing any of his charges into the fray.
"I think the freshness is good," he explained. "If you trust players and believe in them, then why not play them? There's not a player I'm reluctant to play.
"Everybody can take part in the games, without question. When we played West Ham at home, I was surprised by how strong a side Sam Allardyce put out that night, but we made 10 changes and they played really well. It was a good performance and I was quite pleased with that. I made 10 other changes the next week.
"It's simply because these are international footballers. There's only Alexander Büttner and Nick Powell who don't have full senior caps. Nick Powell's had an injury for the last few weeks, although he's back in training now. He's one player who could make a difference to us. He's a talented boy. Büttner's also settled in very well, but he's not an international. But everyone around about him is, so why not play him?"