The former Northern Ireland international scored the Boxing Day winner in Sir Alex Ferguson's first-ever meeting with the Merseysiders and hit the net four times in total against the all-conquering 'Pool before joining Everton in 1989.
Despite the emergence of champions Manchester City as a force in recent years, the visit of Brendan Rodgers' side on Sunday is bound to stir the passions like no other game at Old Trafford this term.
"It's the first date you look for when the fixture list comes out," Whiteside told ManUtd.com. "Not just as players but supporters too.
"I still think it's the biggest game of the season. I know City are coming close to it but they still have a long way to go. If you're looking at United and Liverpool with 19 and 18 league titles, then City are a long way off that and well behind as far as history is concerned."
Whiteside believes it is difficult to predict the outcome on Sunday, even if United go into the big game in good heart after Robin van Persie's late strike avoided an early FA Cup exit at West Ham. Following the 2-1 triumph at Anfield last September, Sir Alex's side are on course to complete the double over the eighth-placed Merseysiders in the first Old Trafford fixture of 2013.
"It's always tough against Liverpool," Whiteside added. "I think all the form books go out of the window.
"It's going to be about whoever is up for it on the day and I just hope we are.