Roy Hodgson has called up 28 players for the games against Chile, on Friday 15 November, and Germany the following Tuesday.
Welbeck and Rooney completed both of England's World Cup qualifiers in October, while Carrick and Smalling also started in the second, the win over Poland that sealed qualification for the World Cup in Brazil next year.
Scoring against both Poland and Montenegro put Rooney onto a total of 38 goals for his country, fifth in England's all-time list and 11 behind rankings leader and United legend Sir Bobby Charlton.
Both England's opponents have also qualified for next year's tournament in Brazil, and while England have not faced Chile since 1998, it is just over three years since Germany knocked Fabio Capello's side knocked out of the last World Cup.
England squad: Fraser Forster, Joe Hart, John Ruddy, Leighton Baines, Gary Cahill, Ashley Cole, Kieran Gibbs, Phil Jagielka, Glen Johnson, Phil Jones, Chris Smalling, Kyle Walker, Ross Barkley, Michael Carrick, Tom Cleverley, Steven Gerrard, Jordan Henderson, Adam Lallana, Frank Lampard, James Milner, Andros Townsend, Jack Wilshere, Jermain Defoe, Rickie Lambert, Jay Rodriguez, Wayne Rooney, Daniel Sturridge, Danny Welbeck.
Wilfried Zaha and Michael Keane have got the nod for England's Under 21 qualifiers against Finland and San Marino. Jesse Lingard and Nick Powell, on loan at Birmingham City and Wigan Athletic respectively, have also caught the eye of recently-installed England U21 coach Gareth Southgate.