United have an uphill task after first-leg defeat...
Date, time, coverage
Thursday 15 March 2012, 18:00 GMT kick-off. Live on Channel 5. You can also follow live on ManUtd.com with text and radio commentary.
United didn't heed Sir Alex's European wake-up call as the form in both the Champions League and Europa League has been below par. The Reds have performed a little better on the road in the competitions after struggling at home and a repeat of the 2-0 win at Ajax would be enough to overturn the first-leg deficit. In the Barclays Premier League, a fine run has seen the champions overtake Manchester City at the top of the table. Athletic Club suffered a 2-1 defeat to Osasuna on Sunday night but have won their last four games at home and are in splendid form. Marcelo Bielsa's men have only lost twice all season at their San Mames home.
Ins and outs
We expect to know exactly who is flying to Spain from 10am on Wednesday morning. Chris Smalling missed out with a head injury against West Brom but Tom Cleverley returned as a substitute and should definitely be available. Sir Alex said recently he expects Antonio Valencia to make his comeback in this fixture. For the hosts, Fernando Amorebeita is back from suspension, which could release Javi Martinez into midfield. Keeper Gorka Iraizoz is set to retain his place between the posts.
The home leg didn't go as planned with the visitors putting on a tremendous performance to take a 3-2 lead to Bilbao. Wayne Rooney's opener was overturned by goals from Fernando Llorente and Oscar De Marcos and a late strike by the outstanding Iker Munaian looked to have effectively dumped United out of the competition. However, a Rooney