Warren Joyce pledged that his side would not ease up during the run-in, mindful of the national play-off against Aston Villa and Manchester Senior Cup final against City being on the horizon, and a 4-1 victory at Chelsea proved the players are following his orders.
The game goes ahead as planned after a 5pm pitch inspection following torrential rain in the Altrincham area, although conditions are expected to be testing.
"When I think back to last year, we got more points than anybody else in the country in all the leagues and then ended up not winning the play-off but there’s enough satisfaction about the consistency in the league really," Joyce told ManUtd.com.
"So it’s just pleasing if you can get consistency over the season. That is the main thing as it means the players are developing. Anything can happen in knockout football so, first and foremost, we’ll look at the remaining league games and end with the same level of consistency that we’ve had all season."
The Reds are 10 points clear of second-placed Liverpool with two games in hand on the Merseysiders. The clash with Wolves is United's first home game at this level since 22 March and will give the fans at Moss Lane their first view of the side since the championship was secured.
Top scorer Will Keane has more goals at Reserves level than anybody else in the country this season and will look to add to his league tally of 15 and seven in his last five matches. Matty James returns after missing the last few games in