United's Reserves have rearranged three fixtures and also confirmed participation in the Dallas Cup.
Warren Joyce's table-toppers will be away in the United States between 29 March and 10 April and could face the likes of Boca Juniors and PSG. The Reds last entered the competition in 2006 and it is the 33rd year of the oldest football tournament in the USA.
“We are very much looking forward to travelling to Dallas to participate in the Dallas Cup," said Joyce. "We will be bringing a team that have been together for a while, a majority of which were involved in winning the Youth Cup last season. It is good experience for the lads to play teams from different cultures and it is a great opportunity for us all."
United's second string will now also play Everton on Monday 26 March at Goodison Park and Newcastle on Tuesday 17 April, with the Stockport clash switched to Carrington on Friday 13 January, behind closed doors.
Stockport (H) 13 January, Carrington 12pm
(Manchester Senior Cup - Behind closed doors)
Everton (A) 26 March, Goodison 7pm
Dallas Cup trip: 29 March - 10 April
Newcastle (A) 17 April, Northumberland FA 7pm