United entertain Aston Villa in the Barclays Under-21 Premier League on Monday night at Moss Lane.
Warren Joyce's side picked up an important three points at Newcastle last week but still trail leaders Tottenham in the table.
The squad making the trip to Turkey ahead of the Champions League encounter at Galatasaray has deprived Joyce of a number of options - including the likes of Davide Petrucci, Ryan Tunnicliffe and Larnell Cole.
Angelo Henriquez is available again following his international commitments for Chile saw him score at senior international level for the first time after being forced to miss the hard-fought victory on Tyneside.
Villa, traditionally strong at this level, defeated Sunderland 2-1 in their last outing.
Squad (from): Jonny Sutherland, Pierluigi Gollini; Frederic Veseli, Luke McCullough, Michele Fornasier, Reece James, Liam Grimshaw, Donald Love; Bebe, Charni Ekangamene, Adnan Januzaj, Luke Hendrie, Mats Daehli, Ben Pearson; Tom Lawrence, Angelo Henriquez, Jack Barmby.
The action is exclusively live on MUTV.