The North Londoners suffered a blow when Kaboul limped off soon after the restart but went close with a Ceballos free-kick that clipped the top of the bar. The near-miss seemed to spur United into action as the hosts produced a spell of flowing football that led to the deadlock being broken.
Januzaj latched onto a through ball by the lively Lingard but was denied by a block from Vigouroux in a one-on-one situation. Seconds later, Tunnicliffe bore down on goal after good play by James and Lingard, managed to beat former colleague Zeki Fryers, and prodded past Vigouroux to open the scoring.
Although Shaquile Coulthirst forced one save out of Amos, the Reds were now in full flow and should have extended the lead. Larnell Cole stormed down the middle to tee up Lingard, only for Vigouroux to stick out a big hand as the winger attempted to take the ball around him. Cole then tried his luck himself but his shot cannoned off the far post with Vigouroux well beaten.
There was no let-up and Tunnicliffe fed Cole again but, although chipping was the right option, he could not get the correct trajectory on his shot and Vigouroux saved comfortably. Januzaj felt he should have had a penalty after substitute Blackett was withdrawn through injury and dazzled with some of his footwork.
United were able to keep Spurs at bay to keep yet another clean sheet this level and move above Liverpool into second place in the table - five points behind the capital club with a game in hand. Friday's fixture at Old Trafford against the Merseysiders has, however, been postponed due to Liverpool's involvement in the FA Youth Cup.
An attendance of 2,183 was impressive and the supporters could not complain after many caught a sight of Sir Alex in the stand and saw a fine display by the young United side.
United: Amos; Veseli (Blackett 10, Lawrence 84), Thorpe, Fornasier, Vermijl; Lingard, Ekangamene, Cole, James; Tunnicliffe; Januzaj. Subs not used: Sutherland, Hendrie, van Velzen.