The Reds will be at home at the Sports Village ground in the UEFA Youth League later this month when Shakhtar Donetsk provide the opposition but will be out to upset the hosts Rovers on this occasion with the game live on MUTV.
Warren Joyce's side have not won in the competition since beating Bolton Wanderers in mid-September but have only played three times since then, drawing twice before losing to Stoke City in a behind-closed-doors fixture.
The options at this level have been reduced by some loan activity on Thursday with the Keane twins (Michael and Will) and Tom Lawrence departing on a temporary basis. The fact that Ben Amos has been farmed out to Carlisle United also means Sam Johnstone looks likely to start.
Joyce is keen to inject some young blood into his line-up, although this is complicated by participation in the aforementioned Under-19 European competition, but Darren Fletcher could continue his push for first-team inclusion with another run-out in midfield.