Story updated 18:30 GMT
Despite snow falling in Manchester earlier in the day, the pitch at Altrincham FC's Moss Lane ground was passed fit, giving local fans and MUTV viewers the chance to watch a strong side featuring senior squad members Anderson and Chris Smalling.
Opponents Wolves proved their worth with a fine victory against group leaders Tottenham recently and should provide another stern test for Warren Joyce's team.
Jeff Schlupp has returned to Leicester and played in the Championship game against Sheffield Wednesday, lining up alongside Michael Keane in defence. As a consequence, Nick Powell looks set to continue in attack after his double saw off West Ham in the last outing.
The full United line-up is as follows, in numerical order: Johnstone, Vermijl, Buttner, Veseli, Thorpe, Smalling, Cole, Anderson, Powell, Januzaj, Lingard. Subs: Gollini; Ekangamene, McGinty, Blackett, Lawrence.
The match, which kicks off at 19:00, is exclusively live on MUTV.