Warren Joyce's side drew 0-0 at fourth-placed Everton last week with Anderson and Fabio among the starters. With a Capital One Cup tie against Norwich City taking place at Old Trafford on Tuesday, Joyce's selection could be affected depending on David Moyes' plans for the Canaries.
Ben Amos starred in the Goodison Park stalemate while Michael Keane and Tom Thorpe will be hoping their performances at the heart of defence have been catching the eye of Moyes, a regular watcher of football at this level.
United lie 16th in the 22-team table but largely because many of the other clubs in the nationwide division have played double the champions' tally of four games.
Fulham are unbeaten and sit third on the back of winning the Under-18 title last summer. Highly-rated former PSG forward Moussa Dembele could be a danger man after netting twice in the last outing, a 2-2 draw with Newcastle.
The match, which kicks off at 7pm GMT, is being screened exclusively live on MUTV.