United’s Academy side will kick off the 2008/09 season with a trip to West Ham on Saturday 23 August.
The U18s, managed by Paul McGuinness, finished third in last season’s Premier Academy Group C, behind Everton and champions Manchester City.
But all eyes are on the future and McGuinness hopes to build on 2007/08.
“We had a stop-start season,” McGuinness told ManUtd.com. “But all the players will come back older and wiser. You learn from experience, good or bad.
“There were good experiences, but we also lost three games by five goals. That shouldn’t happen to our teams.”
The Reds’ first home game sees United welcome Norwich City to the Trafford Training Centre on Saturday 30 August.
Manchester derbies occur Saturday 6 Dec (home) and Saturday 14 February (away), while the U18s face Liverpool on Saturday 18 October (home) and Saturday 13 December (away).
Fans can watch the majority of Academy games on MUTV.
For full fixtures, click here.