Ben Pearson scored the winner, seven days after opening the scoring in the 2-1 home loss to Stoke City. He was joined on the Reds' scoresheet by Nuneaton-born defender Louis Rowley, the club's Young Player of the Year Mats Daehli and young Northern Irish midfielder Paddy McNair.
Rowley got the ball rolling for the Reds at Spurs' training ground, heading home at the back post. The same United player was inadvertently involved in the hosts' first equaliser, deflecting a cross past his own goalkeeper Pierluigi Gollini.
The woodwork was rattled at both ends with the score at 1-1, the Reds hitting the bar from a free-kick before Spurs struck a post. The teams then traded goals again with Daehli putting United in front only for the home side to level it for half-time at 2-2. In between, the lively James Wilson almost made it 3-1 to the visitors when he went around the goalkeeper but hit the upright.
Spurs were up in arms, vainly claiming offside, when McNair restored the Reds' lead from close range and although they soon avenged this with a third equaliser, they could find no fourth reply when Pearson finally made it 4-3 to United.
United: Gollini; Love, Grimshaw, McNair, Rowley; Weir, Pearson (McConnell 85), Rothwell, Daehli; Byrne (Dalley 61), Wilson. Subs not used: Sutherland.