The result was tough on the young Reds, who had looked the better side without really threatening to score the crucial opener. Olexander Zinchenko netted at a time when United were starting to need to commit extra men forward in search of a goal and, although Ashley Fletcher levelled with four minutes left to spark a frenetic finale, there was no fairytale ending.
The first half was a mostly cagey affair but Pierluigi Gollini was forced to make a vital save after only 12 minutes. The Reds were caught napping following a Zinchenko free-kick and Artur Miranyan was left in the clear, only for Gollini to make a superb block.
Although Viktor Kovalenko also forced a routine stop out of United's Italian goalkeeper, the hosts looked a threat although Andreas Pereira was unable to profit after being put clear by James Wilson. After Josh Harrop was unable to release Wilson, the skipper later displayed neat footwork after being picked out by Joe Rothwell but could only produce a wayward finish.
Sean Goss had a shot blocked and Wilson turned Taras Kacharaba beautifully to fire powerfully across goal as Nicky Butt's side shaded the opening period in front of a crowd of 1,903.
In the second half, Wilson won the ball from Mykola Matviyenko, only for the defender to barge him over inside the box with the referee waving away penalty appeals. There was a shout at the other end soon afterwards but Andriy Boryachuk was rightly booked for diving after Gollini did not appear to make any contact.