The Singha 80th Anniversary Cup is at stake when David Moyes fields a United team for the first time ever at the Rajamangala Stadium.
Wayne Rooney has joined the likes of Nemanja Vidic, Nani, Chris Smalling and Ashley Young on the injured list but there is still a wealth of talent at the new manager's disposal. Danny Welbeck looks a certain starter as the sole out-and-out striker left in the squad but there is real competition for places elsewhere.
Anders Lindegaard is expected to keep goal while experienced figures such as Patrice Evra, Rio Ferdinand, Ryan Giggs and Michael Carrick will bring their qualities to the team. Recent recruit Wilfried Zaha will be handed his first outing in a Reds shirt providing he has fully recovered from the ankle injury that hampered his impact at the Under-21 European Championship.
Players from Muangthong United and Buriram United are expected to form the backbone of the All Stars' line-up with Dr Vichit Yamboonruang and Piyapong Pue-on taking charge of the team.
MUTV is screening the match exclusively live on Saturday.