Jesse Lingard runs between Sergio Aguero and Benjamin Mendy.

Your essential guide to the Manchester derby

All eyes will be on Old Trafford when Manchester United face Manchester City in the Premier League on Wednesday.

The Reds need to respond after the 4-0 loss to Everton on Sunday, but face a City side who are gunning for a second successive title.

A home win could derail those hopes and would strengthen our top-four aspirations, which were boosted over the weekend with all three rivals Arsenal, Chelsea and Tottenham Hotspur dropping points.

Here is what you need to know ahead of the derby...

United v City: Manchester derby details
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Wednesday 24 April | Premier League | Old Trafford | 20:00 BST kick-off | Live build-up on MUTV from 18:30 BST | Referee: Andre Marriner

HOW CAN I FOLLOW THE GAME?

Wednesday's game kicks off at 20:00 BST and will be shown live on Sky Sports in the UK. MUTV subscribers will be able to watch live build-up ahead of the match from 18:30 BST, and you can also follow our usual coverage on ManUtd.com and in the official Manchester United App, which is available to download here.

WHAT'S THE TEAM NEWS?

Luke Shaw is back from suspension and looks certain to start at left-back, but Phil Jones sustained an injury at Everton and may miss Wednesday's match. Ander Herrera, Eric Bailly and Antonio Valencia have been out of action for several weeks, but Alexis Sanchez is now back in the fold after recovering from a knee problem. For the visitors, manager Pep Guardiola has confirmed that City will be without Kevin De Bruyne at Old Trafford. Asked in his pre-match press conference about the influential Belgian, the City boss said: “I don’t know. It’s a muscular problem we will see in next days how he will do but tomorrow, no.” The visitor's only other injury concern is back-up keeper Claudio Bravo, who is a long-term absentee.

HOW GOOD ARE CITY?

The Blues are in outstanding form but their hopes of a quadruple were dashed when Tottenham Hotspur eliminated them from the Champions League last week. Our neighbours have already won the Carabao Cup and will face Watford in the Emirates FA Cup final at Wembley Stadium next month.

In the league, City have not dropped a point since a shock 2-1 defeat at Newcastle United in January, winning 10 games on the trot. Their most recent three points came against Spurs as they avenged the European exit with a 1-0 victory last Saturday, thanks to Phil Foden's early header.

WHAT IS THE CONTEXT OF THE GAME?

City know if they keep their current run going, they will win the league. However, Liverpool are also on a fine run and are waiting in the wings to profit from any slip-up. Indeed, the Merseysiders are currently top of the table, having played a game more. For United, our aim is simple - to get into the top four. Yet the heavy loss at Everton has placed even greater importance on pulling off a win in the derby, in order to boost our hopes of playing in next season's Champions League.

Classic encounter: United 4 City 3 (2009)
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Michael Owen netted an injury-time winner to ensure United took all three points in a goal-laden derby. Wayne Rooney and Darren Fletcher (2) were also on target for the Reds.

WHAT'S OUR RECORD LIKE IN THE DERBY?

The Reds have won 72 times, drawn 52 games and lost 52 others. We triumphed in a classic derby 3-2 at the Etihad Stadium last season, postponing the home side's title celebrations despite trailing 2-0 at the break.

At Old Trafford, our form has not been good - despite a Juan Mata goal sealing a League Cup victory in October 2016. A 4-2 success in April 2015, with Ashley Young, Marouane Fellaini, Mata and Chris Smalling on the scoresheet, was the last time we took three points from a home fixture.

WHO'S THE REFEREE?

Andre Marriner will take charge of what is surely set to be a hotly contested encounter. The experienced official has overseen three United matches this season - the last of which was January's 2-0 victory at Newcastle - however, this will be the first Manchester derby that the 48-year-old has overseen since 2012. Marriner will be assisted by Scott Ledger and Simon Long, while Craig Pawson will assume the role of fourth official.

Referee Andre Marriner
Andre Marriner will take charge of his third Manchester derby.

RIVALS WATCH

Tottenham Hotspur meet Brighton & Hove Albion at their newly refurbished stadium on Tuesday night, while Arsenal travel to Wolves - a side who have proven their mettle against the top sides - the following day.

Tuesday:
Tottenham Hotspur v Brighton & Hove Albion
Watford v Southampton 

Wednesday:
Wolverhampton Wanderers v Arsenal 
Manchester United v Manchester City (20:00 BST)

All kick-off times are 19:45 BST unless stated otherwise.

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