What we know about tonight's team

For those who play our United Predictions game, the hints that have already been dropped should provide a strong base for having a good stab at the XI on duty for the final Group F fixture, with the Reds already assured of a seeded slot in the round-of-16 draw next Monday.

With the domestic matches coming thick and fast throughout the month, our interim manager has indicated that he will rotate his squad, and, although there are still many questions to be answered, some of the proposed side has already been revealed.

So let's start in goal as we know Dean Henderson is primed to start, with the boss admitting as much during his press conference. The homegrown keeper is set to make his second senior appearance of the season after a lay-off from the after-effects of COVID-19 at the beginning of the campaign. He also played, and performed well, in the Carabao Cup tie against West Ham United.

Henderson made one outing in this competition last term, the away defeat to Istanbul Basaksehir, and another four in the Europa League, conceding only once across the double-headers with Real Sociedad and AC Milan.

Aaron Wan-Bissaka is ready to regain the right-back role after missing the win over Arsenal with a hand problem but being on the bench for the 1-0 triumph against his former club Crystal Palace. Both full-backs could change as Luke Shaw is also likely to return from a head injury sustained at Watford, with the England man due to replace Alex Telles if he proves his fitness.

Nemanja Matic is set to captain the side for the second time this campaign, pointing towards Harry Maguire being rested. The centre-back positions need to be finalised and it remains to be seen if Victor Lindelof also steps down, with Eric Bailly definitely a potential starter. Phil Jones is ineligible, though, and Rafael Varane has been ruled out. Teden Mengi is available as part of the Champions League squad.

Matic appears certain to land one of the defensive midfield roles and Donny van de Beek, another confirmed starter, could either play alongside the Serbian or in one of the more advanced positions if Ralf sticks with the 4-2-2-2 formation that proved successful against Palace.

Two other midfielders, Jesse Lingard and Juan Mata, strong contenders for one of the more advanced slots, will also get game-time, although Rangnick did not say if they would definitely be in the XI or come off the bench. Youngsters Anthony Elanga and Amad are also in the interim manager's thoughts but we know Mason Greenwood is to play in attack.

The 20-year-old got his first minutes after testing positive for COVID-19 when coming on as a substitute and recording the assist for Fred's winner on Sunday.

With Anthony Martial joining Edinson Cavani on the sidelines, although both could be available again next week, the options are more limited than usual and there is talk in some quarters that Cristiano Ronaldo could feature, at least at some point, as he is on the brink of scoring in each of the six group games. However, it may be decided that our leading marksman deserves a rest.

Rangnick is keen to have a close look at his squad as he bids to implement his ideas swiftly and there are clearly very positive early signs with regards to his faith in youth. In addition to Elanga coming on at a critical time of the Palace match, the club has also promoted six Academy youngsters onto the B list for the competition ahead of the 20:00 GMT kick-off.

Bjorn Hardley, Zidane Iqbal, Sam Mather, Charlie Savage, Charlie Wellens and Shola Shoretire have been added, which may have some impact on the Under-19s' final UEFA Youth League group game, with Young Boys providing the opposition at Leigh Sports Village in a 15:00 GMT kick-off.

Hannibal is currently representing Tunisia in the Arab Cup.